Marlene was friends with Ellie's mom, but I feel that there's something more to it than friendship. At the end of her recording, she says she misses Anna (Ellie's mom) but the way she said makes me think she could've loved her. I'm just speculating, but to me, the way that she said makes me think that she wanted to be more than just friends with Ellie's mom. I could be wrong; in fact, I probably am wrong, but that's what I think. Just listen to the recording real close and see if you get what I mean.
The article clearly states that Marlene is the "main and final antagonist" in the game, but is this really the case? I feel it's pretty ambigous as to whose motivations are right and whose wrong by the end of the game, so painting Marlene as a bad guy just seems odd. Not to mention the general character distinction as "The Bad" and "The Good" which is kind of contrived for this game.
True, Marlene's status as an antagonist can be debated for obvious reasons. Maybe it's better to leave that part out...
Reading too much into the quote? Edit
The current edit takes a look at the surgeon's comments, "All the sacrifices of those men and women or worse, will not be in vain". I don't think this is referring to prior immune subjects but more a broad one referring to the struggle humanity has had as a whole trying to survive the infection (and vainly attempting to find a cure) and the collapse it caused. --18.104.22.168 09:20, December 29, 2013 (UTC)
The exact quote of the surgeon's comments is: "All of our sacrifices and the hundreds of men and women who've bled for this cause, or worse, will not be vain."
I can't find a way to deduce that Ellie is not the only one immune.
If the hundreds of men and women are the immune people, why will some just bleed and others die [worse] ? Moreover, can't they just keep the "only bleeding guys" and use them for researches? If not, why?
In the end I think that the hundreds of men and women are just all the ones struggling to survive for the future of mankind and not just for themselves, waiting for something ( or someone) to happen and then start working on a way to go back to the lost condition of humanity.